Prothioconazole TC, EC, SC, OD

Prothioconazole TC, EC, SC, OD

Specification of Prothioconazole in FAO SPECIFICATION 745 (October 2021*)

PROTHIOCONAZOLE TECHNICAL MATERIAL

FAO Specification 745 / TC (October 2021*)

This specification, which is PART ONE of this publication, is based on an evaluation of data submitted by the manufacturer whose name is listed in the evaluation report (745/2020). It should be applicable to TC produced by this manufacturer, but it is not an endorsement of those products, nor a guarantee that they comply with the specifications. The specification may not be appropriate for TC produced by other manufacturers. The evaluation report (745/2020) as PART TWO forms an integral part of this publication.

1 Description

The material shall consist of prothioconazole together with related manufacturing impurities and shall be white to beige powder free from visible extraneous matter and added modifying agents.

2 Active ingredient

2.1 Identity tests (CIPAC 745/TC/M/2, CIPAC Handbook P, p. 165, 2021)

The active ingredient shall comply with an identity test and, where the identity remains in doubt, shall comply with at least one additional test.

2.2 Prothioconazole content (CIPAC 745/TC/M/3, CIPAC Handbook P, p. 165, 2021)

The prothioconazole content shall be declared (not less than 970 g/kg) and, when determined, the average measured content shall not be lower than the declared minimum content.

3 Relevant impurities

3.1 2-(1-chlorocyclopropyl)-1-(2-chlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propan-2-ol

Maximum: 0.5 g/kg.

PROTHIOCONAZOLE EMULSIFIABLE CONCENTRATE

FAO Specification 745 / EC (October 2021*)

This specification, which is PART ONE of this publication, is based on an evaluation of data submitted by the manufacturer whose name is listed in the evaluation report ((745/2020). It should be applicable to EC of this manufacturer, and those of any other formulators who use only TC from the evaluated sources. The specification is not an endorsement of those products, nor a guarantee that they comply with the specification. The specification may not be appropriate for the products of other manufacturers who use TC from other sources. The evaluation report (745/2020) as PART TWO forms an integral part of this publication.

1 Description

The material shall consist of technical prothioconazole, complying with the requirements of FAO specification 745/TC (October 2021) together with any other necessary formulants. It shall be in the form of a stable homogeneous liquid, free from visible suspended matter and sediment, to be applied as an emulsion after dilution in water.

2 Active ingredient

2.1 Identity tests (CIPAC 745/EC/M/2, CIPAC Handbook P, p. 169, 2021)

The active ingredient shall comply with an identity test and, where the identity remains in doubt, shall comply with at least one additional test.

2.2 Prothioconazole content (CIPAC 745/EC/M/3, CIPAC Handbook P, p. 169, 2021)

The prothioconazole content shall be declared in g/l at 20 ± 2ºC (Note 1) and, when determined, the average content measured shall not differ from that declared by more than the appropriate tolerance, given in the table of tolerances.

Declared content in g/l at 20 ± 2°C         Tolerance

above 25 up to 100                                    ± 10% of the declared content

above 100 up to 250                                  ± 6% of the declared content

above 250 up to 500                                  ± 5% of the declared content

Note: the upper limit is included in each range

3 Relevant impurities (Note 2)

3.1 2-(1-chlorocyclopropyl)-1-(2-chlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propan-2-ol

Maximum: 0.05 % w/w of the prothioconazole content found under 2.2.

4 Physical properties

4.1 Emulsion stability and re-emulsification (MT 36.3, CIPAC Handbook K, p. 137, 2003)

The formulation, when diluted at 25 ± 2 °C (Note 3) with CIPAC Standard Waters A and D, shall comply with the following:

Time after dilution          Limits of stability, MT 36.3

0 h                             Initial emulsification complete

0.5 h                          "Cream" or “Sediment”, maximum: 1 ml

2.0 h                          "Cream" or “Sediment”, maximum: 2 ml;

                                   "Free oil", maximum: 0.5 ml      

24 h                           Re-emulsification complete      

24.5 h                        "Cream" or “Sediment”, maximum: 1 ml

"Free oil", maximum: 0.5 ml      

Note: in applying MT 36.3, tests after 24 h are required only where results at 2 h are in doubt

4.2 Persistent foam (MT 47.3, CIPAC Handbook O, p. 117, 2017)

Maximum: 60 ml after 1 min.

5 Storage stability

5.1 Stability at 0°C (MT 39.3, CIPAC Handbook J, p. 126, 2000)

After storage at 0 ± 2°C for 7 days, the volume of solid and/or liquid which separates shall not be more than 0.3 ml.

5.2 Stability at elevated temperature (MT 46.4, CIPAC Handbook P, p. 232, 2021)

After storage at 54 ± 2°C for 14 days (Note 5), the determined average active ingredient content must not be lower than 95 % relative to the determined average content found before storage (Note 6) and the formulation shall continue to comply with the clauses for:

- by-products of manufacture or storage (3.1)

- emulsion stability and re-emulsification (4.1),

PROTHIOCONAZOLE SUSPENSION CONCENTRATE

FAO Specification 745 / SC (October 2021∗)

This specification, which is PART ONE of this publication, is based on an evaluation of data submitted by the manufacturer whose name is listed in the evaluation report ((745/2020). It should be applicable to SC of this manufacturer, and those of any other formulators who use only TC from the evaluated sources. The specification is not an endorsement of those products, nor a guarantee that they comply with the specification. The specification may not be appropriate for the products of other manufacturers who use TC from other sources. The evaluation report (745/2020) as PART TWO forms an integral part of this publication.

1 Description

The material shall consist of a suspension of fine particles of technical prothioconazole, complying with the requirements of FAO/WHO specification 745/TC (October 2021), in the form of white to beige powder, in an aqueous phase together with suitable formulants. After gentle agitation the material shall be homogeneous and suitable for further dilution in water.

2 Active ingredient

2.1 Identity tests (CIPAC 745/SC/M/2, CIPAC Handbook P, p. 170, 2021)

The active ingredient shall comply with an identity test and, where the identity remains in doubt, shall comply with at least one additional test.

2.2 Prothioconazole content (CIPAC 745/SC/M/3, CIPAC Handbook P, p. 171, 2021)

The prothioconazole content shall be declared (g/kg or g/l at 20 ± 2ºC, note 2) and, when determined, the average content measured shall not differ from that declared by more than the following tolerances:

Declared content in g/L              Tolerance

above 100 up to 250             ± 6% of the declared content

above 250 up to 500             ± 5% of the declared content

Note: In each range the upper limit is included

3 Relevant impurities

3.1 2-(1-chlorocyclopropyl)-1-(2-chlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propan-2-ol

Maximum: 0.05 % w/w of the prothioconazole content found under 2.2.

4 Physical properties

4.1 Pourability (MT 148.1, CIPAC Handbook F, p. 348, 1995)

Maximum residue: 5%.

4.2 Spontaneity of dispersion (MT 160, CIPAC Handbook F, p. 391, 1995)  

A minimum of 80% of the prothioconazole content found under 2.2 shall be in suspension after 5 minutes in CIPAC Standard Water D at 30 ± 2°C.

4.3 Suspensibility (MT 184.1)

A minimum of 80% of the prothioconazole content found under 2.2 shall be in suspension after 30 minutes in CIPAC Standard Water D at 25 ± 5°C.

4.4 Wet sieve test (MT 185, CIPAC Handbook K, p.148, 2003)

Maximum: 0.2% of the formulation shall be retained on a 75 μm test sieve.

4.5 Persistent foam (MT 47.3, CIPAC Handbook O, p. 177, 2017)  

Maximum: 60 ml after 1 minute.

5 Storage stability

5.1 Stability at 0°C (MT 39.3, CIPAC Handbook J, p.126, 2000)

After storage at 0 ± 2°C for 7 days, the formulation shall continue to comply with clauses for:

- suspensibility (4.4),

- wet sieve test (4.5).

5.2 Stability at elevated temperature (CIPAC 745/FS/M/2, CIPAC Handbook P, p. 169, 2021)

After storage at 54 ± 2°C for 14 days, the determined average active ingredient content must not be lower than 95% relative to the determined average content found before storage and the formulation shall continue to comply with the clauses for:

- by-products of manufacture or storage (3.1)

- pourability (4.1),

- spontaneity of dispersion (4.2),

- suspensibility (4.3),

- wet sieve test (4.4),